Bacterial tape recorder
This paper describes a bacterial tape recorder. E.coli engineered to be a bacterial tape recorder by allowing it change its genome in response to chemical signals. This is one of these mind-blowing...
View ArticleBig data reproducibility issues
This piece explains the inherent challenge of providing statistical significant results out of high dimensional data sets. It also suggests a number of strategies to mitigate the problem. The post Big...
View ArticleMinimal Cell Cycle
This is a great example of a paper where synthetic biology meets systems biology. The authors developed a minimal cell cycle regulatory network by engineering a synthetic CDK. To simplify the cell...
View ArticleModeling a Minimal CDK Network
This paper reports a computational analysis of the minimal CDK network engineered in fission yeast (doi:10.1038/nature09543). It had been observed that a Cdk-inhibitory mechanism working through...
View ArticleTeaching Synthetic Biology with GenoCAD
Teaching synthetic biology can be challenging because it involves concepts from so many fields. I would like to give credit to two professors who have been teaching synthetic biology using GenoCAD. I...
View ArticleSynthetic biology textbooks
I recently came across a couple of synthetic biology textbooks that you may find useful if you have not seen them yet. BioBuilder published by O’Reilly in July 2015. The lead author is Natalie Kuldell...
View ArticleEntrainment of a genetic oscillator
This paper from Bill Mather group in the Physics Department at Virginia Tech shows how a genetic oscillator responds to noisy signals. The authors show that the oscillator gets entrained despite the...
View ArticleRecent cell cycle articles
This page helps you find recent cell cycle articles. All these articles have been mentioned at least once in social media over the last seven days. They are ranked by number of mentions in social media...
View ArticleBiocomplexity Institute
On December 1st, 2015, the Virginia Bioinformatics Institute (VBI) became the Biocomplexity Institute of Virginia Tech. VBI was created 15 years ago, at a time when the acquisition and analysis of...
View ArticleNoise in synthetic genetic oscillators
This paper focuses on characterizing the stochastic dynamics of previously described synthetic genetic oscillators. It is a very nice combination of experimental and computational work. The...
View ArticleEssential Social Media Tools
Many scientists think that they don’t have the time to develop a presence in social media. Like many people in other trades, scientists are busy and cannot spend half of their day on Twitter, Facebook,...
View ArticleMoving to CSU
After 10 years at Virginia Tech, it is not without emotion that I am moving to CSU. I have joined the faculty of the Department of Chemical & Biological Engineering at Colorado State University who...
View ArticleRecent CSU Publications
This is a list of CSU publications referenced in Pubmed. All these publications have one author affiliated with Colorado State University. They have been discussed in social media over the last week....
View ArticleClik here to view.
Noisy foresight
Twenty years ago, I was just a boy with a crazy dream of building stochastic models of the noise affecting the expression of genes in living cells. Back in the 90s this idea sounded like an heresy. The...
View ArticleScientist positions for army contract
A friend of mine works for a defense contractor who is part of a team that recently won a large support contract with the Army Medical Command. They are looking to recruit young scientists in a number...
View ArticleApply to Q-Bio Summer School
There is still time to apply to the 2016 Q-Bio Summer School. Applications are due on Monday, February 16 at 11:59pm (MST). The application requires a CV and a 1-page statement of interest in the...
View Article